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Table 4 Top five list of biomarker candidates correlating most strongly with gait speed change 1 year post-shunting

From: Novel cerebrospinal fluid biomarkers correlating with shunt responsiveness in patients with idiopathic normal pressure hydrocephalus

Accession

Gene symbol

Spearman correlation coefficient R

p-value

FDR-adjusted p-value

P05556

ITGB1

− 0.48

 < 0.001

0.755

P61981

YWHAG

− 0.41

 < 0.01

0.984

O95897

OLFM2

0.39

 < 0.01

0.984

Q15582

TGFBI

− 0.38

 < 0.01

0.984

Q14126

DSG2

0.37

 < 0.01

0.984

  1. List of top five biomarker candidates to predict shunt responsiveness in iNPH patients 1 year post-shunting identified via Spearman rank-order correlation. Protein abundances were correlated with the patient’s corresponding change in gait speed 1 year after shunt installation. P-values were adjusted using Benjamini–Hochberg correction
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Fluids and Barriers of the CNS

ISSN: 2045-8118