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Fig. 3 | Fluids and Barriers of the CNS

Fig. 3

From: Modelling idiopathic intracranial hypertension in rats: contributions of high fat diet and testosterone to intracranial pressure and cerebrospinal fluid production

Fig. 3

Negligible transcriptomic changes in choroid plexus of HFD-fed rats. A illustrates a pie chart of the percentage differentially expressed genes. B A heatmap of the differentially expressed genes in the individual rats, coloured based on the Z-score of normalized fold changes (n = 5 of each). C Volcano plot of all transcripts detected in the choroid plexus of control and HFD-fed rats with differentially expressed genes (Adjusted p-value < 0.05) marked in red (upregulated) or blue (downregulated). D GO enrichment analysis of the protein classes. E Association protein network analysis of the highest order cluster of genes. The protein nodes are coloured based on log2FC (downregulated in blue) and the connecting lines coloured based on the string confidence score from 0.7 (grey) to 1.0 (black)

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