Table 1 Number of mice (n) for each subgroup
From: Age, dose, and binding to TfR on blood cells influence brain delivery of a TfR-transported antibody
[125I]mAb3D6-scFv8D3 |  | [125I]mAb3D6 | Naïve | ||||
|---|---|---|---|---|---|---|---|
WT | Low dose | High dose | Therapeutic dose | WT | Low dose | High dose | In vitro blood study/Western blot |
Young | 10 | 11 | 5 | Young | 3 | 4 | 10 |
Aged | 12 | 13 | Â | Aged | 4 | 8 | 10 |
Tg-ArcSwe | Low dose | High dose | Â | Tg-ArcSwe | Low dose | High dose | Â |
Young | 7 | 7 | Â | Young | 3 | 4 | Â |
Aged | 5 | 7 | Â | Aged | 4 | 5 | Â |