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Fig. 3 | Fluids and Barriers of the CNS

Fig. 3

From: High affinity of β-amyloid proteins to cerebral capillaries: implications in chronic lead exposure-induced neurotoxicity in rats

Fig. 3

Increased Aβ binding to cerebral capillaries following chronic in vivo Pb exposure. A, B Quantification of Aβ40 concentration in cerebral parenchyma and capillaries following in situ brain perfusion of Aβ40. Parenchymal and vascular fractions of specific brain regions were sampled from rats exposed to Pb (14 mg or 28 mg Pb/kg) and controls for 4 or 8 weeks. Data represent mean ± SD, n = 4–8; *p < 0.05, **p < 0.01, as compared to the controls in specific brain fraction; #p < 0.05 as compared to the low Pb exposure group in specific brain fraction. Par. parenchyma fraction, Cap. capillary fraction

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Fluids and Barriers of the CNS

ISSN: 2045-8118