Fig. 4
From: Central nervous system insulin signaling can influence the rate of insulin influx into brain
125I-insulin blood-to-brain transport following intranasal insulin. 125I-insulin BBB pharmacokinetics were assessed 30 min after 1 µl IN injection of vehicle (1% BSA/LR) or insulin (1 µg) in the (A) whole brain, (B) olfactory bulb, and (C) hypothalamus. See Table 1 for pharmacokinetic calculations. Each data point represents a single mouse. Ki *p < 0.05 as marked