Fig. 5

Increased mitochondrial elongation in aged choroid plexus epithelial cells. A Representative TEM images of choroid plexus epithelial cells at 2 and 20 months ols (m.o.). Quantification of intracellular distribution (B), density (C) and sectional surface of mitochondria (D). E High magnification TEM images showing representative mitochondria at 2 and 20 m.o. Quantification of mitochondria circularity score (F) and Feret’s diameter (G). n = 30 cells per animal, 3 animals per age; black dashed line: median. Kruskal–Wallis; *p < 0.05, ***p < 0.001, ****p < 0.0001. Scale bars: 2 µm (A), 500 nm (E)