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Fig. 1 | Fluids and Barriers of the CNS

Fig. 1

From: Concentration gradients of monoamines, their precursors and metabolites in serial lumbar cerebrospinal fluid of neurologically healthy patients determined with a novel LC–MS/MS technique

Fig. 1

Concentrations of monoamines, their precursors and metabolites in five consecutive CSF fractions. Concentrations of A L-DOPA (levodopa), B 3-OMD (3-o-methyldopa), C DA (dopamine), D DOPAC (3,4-Dihydroxyphenylacetic acid), E 3-MT (3-methoxytyramine), F HVA (homovanillic acid), G NA (noradrenalin), H NMN (normetanephrine), I MOPEG (3-Methoxy-4-hydroxyphenylglycol) and J 5-HIAA (5-hydroxyindoleacetic acid) for the five consecutive fractions of CSF: 1: 0–2 mL, 2: 2–4 mL, 3: 4–6 mL, 4: 6–8 mL, 5: 8–10 mL. For all analytes, the bold line shows the median concentration and the grey box the IQR. Concentration gradient for analytes significant at 0.05 level (*), 0.01 level (**) or 0.001 level (***)

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