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Fig. 3 | Fluids and Barriers of the CNS

Fig. 3

From: Effects of bacterial and viral pathogen-associated molecular patterns (PAMPs) on multidrug resistance (MDR) transporters in brain endothelial cells of the developing human blood–brain barrier

Fig. 3

Poly I:C increased P-gp protein levels in second trimester human primary fetal brain endothelial cells (hfBECs). A Representative Western blot images and, B–G densitometric analysis of P-gp total protein levels, normalized to ERK2 (loading control for total protein), in early and mid-gestation hfBECs following treatment with LPS (0.01 µg/mL), Poly I:C (1 µg/mL), ssRNA (0.001 µg/mL) or vehicle for 24 h. Data are expressed as means ± SD. N = 6/group (if N < 6, an outlier has been removed). Statistical differences were tested using a paired t-test. *p < 0.05

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Fluids and Barriers of the CNS

ISSN: 2045-8118