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Fig. 6 | Fluids and Barriers of the CNS

Fig. 6

From: Modulation of striatal glutamatergic, dopaminergic and cholinergic neurotransmission pathways concomitant with motor disturbance in rats with kaolin-induced hydrocephalus

Fig. 6

Dendritic spine density analyses of the intracellular dye-filled d and i-MSNs. A, B are analyses of the d and i-MSNs respectively. The tissue was also processed with substance P immunohistochemistry to distinguish between d and i-MSNs. In each panel, representative proximal and distal dendritic segments of the intracellular dye-filled neurons are shown at the top while the histogram of the corresponding analysis at the bottom. Numbers of dendritic segments, neurons, and rats studied in this part of the experiments are in Table 1. Con, control; Hydro, hydrocephalus; d-MSN, direct-pathway medium spiny neuron; i-MSN, indirect-pathway medium spiny neuron. *P < 0.05 and **P < 0.001 between the marked and the corresponding age-matched control. $$P < 0.001 between the age-matched control rats of the chronic and acute groups. Scale bar = 10 μm

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Fluids and Barriers of the CNS

ISSN: 2045-8118