Fig. 3

Blood and its breakdown products do not hyperactivate NKCC1 or the Na⁺/K⁺-ATPase in ex vivo choroid plexus. a Loss of ⁸⁶Rb⁺ from the choroid plexus shown as efflux rate constants for ⁸⁶Rb⁺ in control (n = 4) and after acute exposure to blood (20% of surrounding fluid, n = 4). b Efflux rate constants for ⁸⁶Rb⁺ in control and after acute exposure to 50 µM hemin (n = 4 of each). c ⁸⁶Rb⁺ influx in control and after acute exposure to blood (20% of surrounding fluid), n = 6–7. d ⁸⁶Rb⁺ influx in control and after acute exposure to 50 µM hemin (n = 5 of each). e Efflux rate constants for ⁸⁶Rb⁺ in control and after long-term exposure (16 h) to blood (20% of surrounding fluid), n = 4 of each. f Efflux rate constants for ⁸⁶Rb⁺ in control and after long-term exposure (16 h) to 50 µM hemin (n = 4 of each). g ⁸⁶Rb⁺ influx in control and after long-term exposure (16 h) to blood (20% of surrounding fluid), n = 5 of each. h ⁸⁶Rb⁺ influx in control and after long-term exposure (16 h) to 50 µM hemin (n = 5 of each). Error bars represent standard deviation and statistical significance was tested with an unpaired two-tailed t-test. **P < 0.01, NS not significant