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Table 3 Linear regression with shunt surgery outcome (delta scores) as dependent variables and radiological volumes as independent variables

From: White matter changes should not exclude patients with idiopathic normal pressure hydrocephalus from shunt surgery

Delta score Volume Unadjusted Adjusted n
   B P-value B P-value  
Delta total iNPH score PVH − 1.260 0.0269* − 1.173 0.0309* 253
DWMH − 0.816 0.0899 − 0.761 0.0896 253
Lateral ventricles 1.752 0.501 4.002 0.229 253
Delta balance score PVH − 0.557 0.357 − 0.365 0.518 238
DWMH − 0.481 0.35 − 0.086 0.856 238
Lateral ventricles 0.873 0.756 3.911 0.259 238
Delta continence score PVH 0.048 0.959 − 0.020 0.982 235
DWMH − 0.241 0.755 − 0.183 0.809 235
Lateral ventricles 4.600 0.282 13.337 0.0175* 235
Delta gait score PVH − 2.148 0.00352** − 2.068 0.00314** 252
DWMH − 1.071 0.0861 − 1.073 0.0636 252
Lateral ventricles 1.172 0.729 0.157 0.971 252
Delta cognitive score PVH − 0.042 0.95 0.047 0.944 95
DWMH − 0.632 0.263 − 0.659 0.231 95
Lateral ventricles 0.564 0.86 0.690 0.875 95
Delta MMSE score PVH − 0.201 0.0703 − 0.146 0.196 241
DWMH − 0.128 0.167 − 0.059 0.519 241
Lateral ventricles 1.242 0.0138* 1.283 0.063 241
  1. Data are adjusted for age, gender, time between preoperative evaluation and surgery, preoperative total iNPH scale score, Evans’ index, and DESH
  2. iNPH idiopathic normal pressure hydrocephalus, DESH disproportionately enlarged subarachnoid space hydrocephalus, B unstandardized regression coefficient, PVH periventricular hyperintensities, DWMH deep white matter hyperintensities, MMSE mini-mental state examination. Bold values are significant, * < 0.05, ** < 0.01