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Fig. 6 | Fluids and Barriers of the CNS

Fig. 6

From: A novel chronic dural port platform for continuous collection of cerebrospinal fluid and intrathecal drug delivery in free-moving mice

Fig. 6

Acute intrathecal administration of drug via CDP and behavioral assessment in the free-moving mouse. a Time course of the experiment. Anesthetic agent (midazolam) was acutely injected via CDP in the free-moving mice (5 µL in 1 s through a syringe connected to the CDP), while locomotor activities were quantitatively measured by the infrared light beam crossing system. b Locomotor activity after the intrathecal administration of anesthetic agent via CDP in the free-moving mice. n = 4/group. Data are presented as the mean ± SEM. CDP chronic dural port

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