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Fig. 3 | Fluids and Barriers of the CNS

Fig. 3

From: Processing mechanism of guanidinoacetate in choroid plexus epithelial cells: conversion of guanidinoacetate to creatine via guanidinoacetate N-methyltransferase and monocarboxylate transporter 12-mediated creatine release into the CSF

Fig. 3

Functional expression of GAMT in TR-CSFB3 cells. Typical chromatograms of A [14C]GAA and B [14C]creatine. C A typical HPLC chromatogram of the cell lysate of TR-CSFB3 cells. TR-CSFB3 cells were incubated with the medium containing [14C]GAA (18.2 µM) for 24 h at 37 °C and the cell lysate of these cells was separated by high-performance liquid chromatography (HPLC)

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