Table 1 Model parameters
From: Arterial vasodilation drives convective fluid flow in the brain: a poroelastic model
Parameter | Value | Unit | Description | Sources |
|---|---|---|---|---|
\({\rho }_{f}^{*}\) | \(1000\) | \({\text{kg}}/{\text{m}}^{3}\) | Fluid true density | |
\({\rho }_{s}^{*}\) | \(1000\) | \({\text{kg}}/{\text{m}}^{3}\) | Solid true density | [5] |
\({\mu }_{f}\) | \(0.001\) | \({\text{Pa}} \, {\text{s}}\) | Fluid dynamic viscosity | |
\({\zeta }_{{R}_{f}}^{2}\) | \(0.2\) | Â | Fluid volume fraction in tissue | |
\({\zeta }_{{R}_{f}}^{1}\) | \(0.8\) | Â | Fluid volume fraction in PVS | Â |
\({k}_{s}^{2}\) | \(2\times {10}^{-15}\) | \({\text{m}}^{2}\) | Fluid permeability of ECS | |
\({k}_{s}^{1}\) | \(2\times {10}^{-14}\) | \({\text{m}}^{2}\) | Fluid permeability of PVS | Â |
\({\mu }_{s}^{2}\) | \(2\) | \({\text{kPa}}\) | Shear Modulus of brain tissue | |
\({\mu }_{s}^{1}\) | \(20\) | \({\text{Pa}}\) | Shear modulus of connective tissue | Â |
\({R}_{0}\) | \(10\) | \(\upmu {\text{m}}\) | Nominal vessel radius | |
\({D}_{a\beta }\) | \(1.4\times {10}^{-6}\) | \({\text{c}}{\text{m}}^{2}/{\text{s}}\) | Diffusion coefficient of amyloid-β | |
\(\lambda\) | \(1.6\) | Â | Tortuosity of ECS | [105] |