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Fig. 2 | Fluids and Barriers of the CNS

Fig. 2

From: Exploring ITM2A as a new potential target for brain delivery

Fig. 2

ITM2A uptake and internalization of several antibodies (anti-ITM2A, anti-GFP or anti-HA) on HEK293 human and mouse. A, B internalization of anti ITM2A revealed with anti-species Alexa 647 in red on HEK293 hITM2A wt, hITM2A GFP N-Ter and hITM2A GFP C-Ter. C internalization of anti-tag antibodies: anti-GFP A31852 Alexa 647 in red, anti-GFP A11122 revealed with anti-Rabbit Alexa 647 in red and anti-HA 901509 Alexa 488 in green on HEK293 hITM2A wt, hITM2A tag N-Ter and hITM2A tag C-Ter. D internalization of anti GFP A31852 revealed with anti-Rabbit Alexa 647 in red on HEK293 mouse ITM2A

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