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Table 4 Differences of the study parameters between the imaging categories at follow-up

From: Incidental findings of typical iNPH imaging signs in asymptomatic subjects with subclinical cognitive decline

Parameter

Overalla

“atrophy” vs. “normal”b

“atrophy” vs. “iNPH”b

“iNPH” vs. “normal”b

Age (years)

 < 0.0001*

0.0002*

NS

0.0205*

Sex (n)

NS

NS

0.0283*

0.0494*

Education (score)

NS

NS

NS

NS

Alcohol (daily units)

NS

NS

NS

NS

Diabetes (n)

NS

NS

NS

NS

Hypertension (n)

NS

NS

NS

NS

Hypercholesterolaemia (n)

NS

NS

NS

NS

WMH (Fazekas score)

0.0009*

0.0470*

NS

0.0027*

SPPB (score)

NS

NS

NS

NS

TMT-B (sec)

0.0020*

NS

NS

0.0036*

Walking speed (m/s)

NS

NS

NS

NS

Executive function (z-score)

0.0129*

NS

NS

0.0210*

g-factor (z-score)

0.0318*

NS

NS

NS

Memory (z-score)

0.0068*

NS

NS

0.0155*

Visuopractical Skills (z-score)

0.0015*

0.0043*

NS

NS

  1. iNPH idiopathic normal pressure hydrocephalus-associated imaging findings, WMH white matter hyperintensities, SPPB short physical performance balance, TMT-B Trail Making Test B
  2. aKruskal–Wallis test in continuous parameters, Fisher’s exact test or Chi-Squared test in the remaining parameters
  3. bDunn’s test in continuous parameters, Chi-Squared test in the remaining parameters
  4. *significant difference