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Table 3 Characteristics of the subjects in relation to the image category at follow-up

From: Incidental findings of typical iNPH imaging signs in asymptomatic subjects with subclinical cognitive decline

Parameter

“Atrophy”

“Normal”

“iNPH”

Number of subjects

Total (n)

42

63

8

113

Age (years, mean ± SD)

74 ± 7

67 ± 10

77 ± 5

113

Sex (female/male, n)

19/23

32/31

7/1

113

Education (score, mean ± SD)a

2.5 ± 1.0

2.5 ± 1.0

2.0 ± 1.1

113

Alcohol (daily units, mean ± SD)

1.1 ± 1.0

0.8 ± 0.8

0.7 ± 0.8

107

Diabetes (y/n, n)

5/36

4/57

1/6

109

Hypertension (y/n, n)

19/22

33/29

4/3

110

Hypercholesterolaemia (y/n, n)

26/15

43/19

6/1

110

WMH (Fazekas score, mean ± SD)

2.5 ± 1.5

1.8 ± 1.1

3.8 ± 1.6

113

SPPB (score, mean ± SD)b

3.6 ± 0.7

3.8 ± 0.4

3.3 ± 1.0

99

TMT-B (sec, mean ± SD)

139 ± 75

110 ± 48

194 ± 53

109

Walking speed (m/s, mean ± SD)

0.4 ± 0.1

0.4 ± 0.1

0.4 ± 0.1

108

Executive function (z-score, mean ± SD)

− 0.0 ± 0.7

0.2 ± 0.6

− 0.5 ± 0.5

74

g-factor (z-score, mean ± SD)

− 0.3 ± 1.1

0.3 ± 0.9

− 0.8 ± 0.8

72

Memory (z-score, mean ± SD)

− 0.2 ± 1.1

0.2 ± 0.9

− 1.1 ± 0.7

103

Visuopractical Skills (z-score, mean ± SD)

− 0.3 ± 0.8

0.3 ± 0.8

− 0.6 ± 1.2

107

  1. iNPH: idiopathic normal pressure hydrocephalus-associated imaging findings; SD: standard deviation; WMH: white matter hyperintensities; SPPB: short physical performance balance; TMT-B: Trail Making Test B
  2. arange of education score: 1 (homemaker, farmer)—4 (academic career)
  3. brange of SPPB score: 1–4