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Table 4 Underexpressed proteins implicated in myelination

From: Identification of key molecular biomarkers involved in reactive and neurodegenerative processes present in inherited congenital hydrocephalus

Gene name

Sum PEP score

Abundance ratio: (sample) / (control)

Abundance ratio P-value: (sample) / (control)

Breast carcinoma-amplified sequence 1 homolog

79.326

0.51

5.41E-06

Calcineurin subunit B type 1

62.58

0.72

0.045

CD9 antigen

6.995

0.584

0.017

Gap junction gamma-3 protein

18.265

0.324

9.08E-08

Junctional adhesion molecule C

4.494

0.252

7.69E-11

Myelin-associated glycoprotein*

177

0.341

2.22E-14

Myelin proteolipid protein*

42.4

0.324

1.33E-15

Oligodendrocyte-myelin glycoprotein*

28.9

0.667

0.026

Protein NDRG1e

35.044

0.666

0.042

Tetraspanin-2

24.519

0.283

2.36E-11

Tubulin polymerization-promoting protein

84.096

0.674

0.009

  1. Underexpressed proteins in the white matter of hyh mice implicated in myelination in the white matter of hyh mice. All the proteins are present in the class and child classes “myelination”, “axon ensheathment”, and “ensheathment of neurons” (see Table 3). *Proteins involved in oligodendrocyte development and differentiation. For meaning of sum PEP score see Table 2 legend
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Fluids and Barriers of the CNS

ISSN: 2045-8118