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Table 4 Underexpressed proteins implicated in myelination

From: Identification of key molecular biomarkers involved in reactive and neurodegenerative processes present in inherited congenital hydrocephalus

Gene name Sum PEP score Abundance ratio: (sample) / (control) Abundance ratio P-value: (sample) / (control)
Breast carcinoma-amplified sequence 1 homolog 79.326 0.51 5.41E-06
Calcineurin subunit B type 1 62.58 0.72 0.045
CD9 antigen 6.995 0.584 0.017
Gap junction gamma-3 protein 18.265 0.324 9.08E-08
Junctional adhesion molecule C 4.494 0.252 7.69E-11
Myelin-associated glycoprotein* 177 0.341 2.22E-14
Myelin proteolipid protein* 42.4 0.324 1.33E-15
Oligodendrocyte-myelin glycoprotein* 28.9 0.667 0.026
Protein NDRG1e 35.044 0.666 0.042
Tetraspanin-2 24.519 0.283 2.36E-11
Tubulin polymerization-promoting protein 84.096 0.674 0.009
  1. Underexpressed proteins in the white matter of hyh mice implicated in myelination in the white matter of hyh mice. All the proteins are present in the class and child classes “myelination”, “axon ensheathment”, and “ensheathment of neurons” (see Table 3). *Proteins involved in oligodendrocyte development and differentiation. For meaning of sum PEP score see Table 2 legend