Table 2 Measures of CSF tracer movement from intrathecal contrast-enhanced MRI

Spinal transit time (min)

17.2 ± 16.1

14.4 ± 9.6

19.3 ± 14.2

34.1 ± 43.8

14.3 ± 4.4

10.0 ± 2.1

13.7 ± 4.9

13.7 ± 7.5

Qualitative measures (N)

92

23

34

7

7

7

11

3

Ventricular reflux N (%)

 Grade 0

25 (27)

13 (57)

0

1 (14)

3 (43)

1 (14)

6 (55)

1 (33)

 Grade 1

9 (10)

3 (13)

2 (6)

0

1 (14)

0

1 (9)

2 (67)

 Grade 2

12 (13)

5 (22)

0

1 (14)

0

3 (43)

3 (27)

0

 Grade 3

21 (23)

2 (9)

11 (32)

3 (43)

3 (43)

1 (14)

1 (9)

0

 Grade 4

25 (27)

0

21 (62)

2 (29)

0

2 (29)

0

0

Percentage change in tracer enrichment (N)

88

23

30

7

8

6

11

3

4th ventricle

 1 h

1076 ± 1253

403 ± 595

1606 ± 1483^b

443 ± 516

1138 ± 1571

1993 ± 1174^c

847 ± 953

1296 ± 1142^a

 2 h

1495 ± 1185

746 ± 602

2248 ± 1187^c

1397 ± 844^a

1526 ± 1449

2112 ± 1175^b

799 ± 875

1061 ± 1407

 4 h

1414 ± 1112

762 ± 617

2181 ± 1083^c

1411 ± 871^a

1112 ± 1266

1985 ± 1192^b

847 ± 855

698 ± 1031

 6 h

1497 ± 1077

799 ± 642

2318 ± 938^c

1626 ± 747^a

1221 ± 1139

1867 ± 1210^b

844 ± 823

972 ± 1065

 24 h

559 ± 609

169 ± 168

1169 ± 595^c

537 ± 569^b

130 ± 94

555 ± 354^b

160 ± 134

102 ± 00

3rd ventricle

 1 h

430 ± 675

140 ± 379

678 ± 779^b

217 ± 303

563 ± 868

1234 ± 857^c

106 ± 191

62 ± 77

 2 h

728 ± 885

271 ± 451

1099 ± 926^c

870 ± 752^a

739 ± 1031

1626 ± 1341^c

160 ± 197

212 ± 257

 4 h

859 ± 965

332 ± 516

1364 ± 958^c

1158 ± 978^a

760 ± 1034

1774 ± 1397^b

198 ± 285

134 ± 151

 6 h

960 ± 968

419 ± 548

1638 ± 916^c

987 ± 903

724 ± 857

1680 ± 1357^b

253 ± 314

160 ± 39

 24 h

479 ± 584

86 ± 116

1081 ± 543^c

469 ± 383^c

103 ± 102

482 ± 575^b

56 ± 73

36 ± 36

Lateral ventricles

 1 h

333 ± 795

119 ± 356

446 ± 1001

245 ± 496

525 ± 1080

1216 ± 1151^b

49 ± 112

7 ± 27

 2 h

850 ± 1332

231 ± 424

1352 ± 1554^b

1047 ± 1300^a

939 ± 1556

1939 ± 2046^b

98 ± 199

245 ± 315

 4 h

1246 ± 1650

393 ± 755

2188 ± 1818^c

1725 ± 1821^a

1018 ± 1583

2176 ± 2263^b

144 ± 305

158 ± 196

 6 h

1461 ± 1687

521 ± 802

2785 ± 1737^c

1338 ± 1447

1019 ± 1327

2125 ± 2097^b

229 ± 433

140 ± 17

 24 h

832 ± 1119

92 ± 188

2038 ± 1062^c

676 ± 615^c

110 ± 114

609 ± 848^b

47 ± 75

49 ± 59