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Fig. 3 | Fluids and Barriers of the CNS

Fig. 3

From: Astrocyte-specific hypoxia-inducible factor 1 (HIF-1) does not disrupt the endothelial barrier during hypoxia in vitro

Fig. 3

Astrocyte HIF-1 paracrine signalling does not affect endothelial cell metabolic activity and proliferation. Graphical representation of EC a mitochondrial activity and b proliferation as measured by BrdU incorporation after 24 h exposure. EC were exposed to normoxic or hypoxic conditions with AC-CM or their own RBE4 media. Data is presented in comparison to baseline controls (normoxic RBE4 media control; red bar). 2way ANOVA, mean ± SD, n = 4–6, *p < 0.05, **p < 0.01, ****p < 0.0001 compared to RBE4 media Nx, ϕp < 0.05 to RBE4 media Hx

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Fluids and Barriers of the CNS

ISSN: 2045-8118