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Fig. 1 | Fluids and Barriers of the CNS

Fig. 1

From: Are CSF CXCL13 concentrations solely dependent on intrathecal production? A commentary on “Chemokine CXCL13 in serum, CSF, and blood–CSF barrier function”

Fig. 1

Serum CXCL13 correlates with CSF CXCL13 levels in NIND patients. CSF and serum CXCL13 (pg/ml) were measured utilizing a human chemokine CXCL13 bead-based immunoassay (Bio-plex Pro™; Bio-Rad, Hercules CA; LLOQ 0.7 pg/ml) in non-inflammatory neurological disease controls (NIND; n = 62). Datasets were tested for normality and were determined to be non-parametric. Correlations were performed comparing serum and CSF CXCL13 values utilizing a Spearman’s rank order correlation for non-parametric data to determine the spearman’s rank correlation coefficient (r) and statistical significance. All statistical analyses were performed using GraphPad Prism version 7.00 (GraphPad, San Diego, CA). P values < 0.05 were deemed to be statistically significant

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Fluids and Barriers of the CNS

ISSN: 2045-8118