Table 4 Signs of blood-cerebrospinal fluid barrier dysfunction: albumin quotients and numbers for female and male patients in relation to reference values
|  | Reference | All patient (N = 989) | Females (N = 545; 55%) | Males (N = 444; 45%) | Statistics |
|---|---|---|---|---|---|
All patients | |||||
 Albumin quotients (× 10–3, Mean ± SD, median and range) |  | 5.81 ± 3.18 5.10 (1.50–38.70) | 5.23 ± 2.56 4.70 (1.50–38.70) | 6.52 ± 3.69 5.70 (2.00–38.30) | F = 52.837 CI = [0.892;1.676] p < 0.001 |
 Increased albumin quotients, numbers of patient |  < 40 y.: < 6.5 × 10–3 40–60 y.: < 8 × 103  > 60 y.: < 9.3 × 10–3 | ↑: 174 (18%)  ↔ : 815 (82%) | ↑: 57 (10%)  ↔ : 488 (90%) | ↑: 117 (26%)  ↔ : 327 (74%) | Chi2 = 42.625 p < 0.001 |
|  | Schizophreniform syndrome (N = 456) | Females (N = 248; 54%) | Males (N = 208; 46%) |  | |
|---|---|---|---|---|---|
Albumin quotients (× 10–3, Mean ± SD) |  | 5.64 ± 3.18 | 5.29 ± 3.02 | 6.06 ± 3.32 | F = 11.906 CI = [0.187;1.354] p = 0.001 |
Increased albumin quotients, numbers of patients |  < 40 y.: < 6.5 × 10–3 40–60 y.: < 8 × 10–3 > 60y.: < 9.3 × 10–3 | ↑: 85 (19%)  ↔ : 371 (81%) | ↑: 33 (13%)  ↔ : 215 (87%) | ↑: 52 (25%)  ↔ : 156 (75%) | Chi2 = 10.200 p = 0.001 |
|  | Affective syndrome (N = 533) | Females (N = 297, 56%) | Males (N = 236, 44%) |  | |
|---|---|---|---|---|---|
Albumin quotients (× 10–3, Mean ± SD) |  | 5.95 ± 3.19 | 5.19 ± 2.11 | 6.92 ± 3.96 | F = 27.991 CI = [1.208;2.260] p < 0.001 |
Increased albumin quotients, numbers of patients |  < 40 y.: < 6.5 × 10–3 40-60 y.: < 8 × 10–3 > 60y.: < 9.3 × 10–3 | ↑: 89 (17%)  ↔ : 444 (83%) | ↑: 24 (8%)  ↔ : 273 (92%) | ↑: 65 (28%)  ↔ : 171 (72%) | Chi2 = 35.808 p < 0.001 |