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Table 1 Summary of clinical data

From: Serum-derived factors of breast cancer patients with brain metastases alter permeability of a human blood–brain barrier model

 

C

PC

VM

BM

CM

Patient characteristics

 Total number

15

26

30

20

12

 Median age

66

57.6

60

66.3

62.1

 Deceased

    

5

 Pre-/postmenopausal

1/14

10/16

6/24

2/18

2/10

Tumour characteristics

 ER/PR positive

 

15

17

16

1

 HER2/neu positive

 

8

11

3

11

 Triple negative

 

2

2

  

Grading

 Well differentiated (G1)

 

2

4

0

0

 Moderately differentiated (G2)

 

18

11

16

6

 Poorly differentiated (G3)

 

6

15

4

6

 % of Ki67 positive cells (median)

 

25%

40%

15%

30%

 Other

    

1

  1. BM bone metastases, C control group of healthy donors, CM cerebral metastases, ER estrogen receptor, Her2/neu human epidermal growth factor 2, PC primary cancer, PR progesterone receptor, VM visceral metastases