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Table 3 Comparison of the two patient groups

From: Secondary deterioration in patients with normal pressure hydrocephalus after ventriculoperitoneal shunt placement: a proposed algorithm of treatment

 

Shunt insufficiency (N = 14)

Secondary non-responder (N = 31)

Test and p-value

Age

 Mean (median) ± SD (at the time of surgery)

68.5 (68) ± 8

73.3 (72) ± 4.2

t-test

p = 0.01

Pre-VPS CMI

 Mean (median) ± SD

2.2 (3) ± 1.8

27 (2) ± 2.3

Mann–Whitney test

p = ns

 Kiefer score

  Mean (median) ± SD

7 (7) ± 3.6

6.8 (7) ± 2.3

Mann–Whitney test

p = ns

New diseases during the F/U (stroke, Alzheimer disease, Parkinson disease)

1 (7%)

6 (19%)

Fisher’s exact test

p = ns

Over-drainage requiring valve pressure setting ≥ 100 mmH2O

0 (0%)

5 (16%)

Fisher’s exact test

p = ns

  1. CMI Comorbidity Index, VPS ventriculoperitoneal shunt, F/U follow-up