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Fig. 3 | Fluids and Barriers of the CNS

Fig. 3

From: Simvastatin, edaravone and dexamethasone protect against kainate-induced brain endothelial cell damage

Fig. 3

The effect of kainate on the permeability of the BBB co-culture model. a Permeability for sodium fluorescein (SF; 376 Da). b Permeability for Evans blue-labelled albumin (EBA; 67 kDa). Treatment with 100 µM kainate (KA) lasted for 1 or 24 h. Control groups (C) received only culture medium. Mean ± SD, n = 4–8, t-test, *p < 0.05, ***p < 0.001 compared to the control group. Permeability is expressed as apparent permeability coefficient (Papp)

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