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Fig. 5 | Fluids and Barriers of the CNS

Fig. 5

From: Enhanced xeno-free differentiation of hiPSC-derived astroglia applied in a blood–brain barrier model

Fig. 5

Protein secretion by hiPSC-derived astroglia differentiated on human, recombinant laminin-521 (LN521) or murine laminin (L2020). ad Concentrations of S100B (a), ApoE (b), angiopoietin-1 (Ang-1) (c) and IL8 (d) were measured in media collected from astroglia differentiated on LN521 or L2020. Secretion of S100B and Ang-1 to the media, were higher in astroglia differentiated on LN521 than astroglia differentiated on L2020, for all lines. The C1 line differentiated on LN521 had higher secretion of IL8 compared to C1 differentiated on L2020. Significance indicated by *p < 0.05, **p < 0.01, ***p < 0.001

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