The endo-lysosomal system of bEnd.3 and hCMEC/D3 brain endothelial cells

Table 1 Number of vesicles per cell

	bEnd.3	hCMEC/D3	p	PBEC	p ^a	p ^b
	Mean ± SEM	Mean ± SEM	p	Mean ± SEM	p ^a	p ^b
Early endosomes	215.98 ± 15.81	147.58 ± 6.18	*	155.71 ± 9.02	#	ns
Recycling endosomes	226.74 ± 9.94	274.80 ± 11.34	ns	134.02 ± 17.00	# #	# # #
Retromer-positive structures	247.18 ± 4.50	158.82 ± 24.74	*	258.64 ± 10.60	ns	# #
Late endosomes	175.83 ± 17.44	83.19 ± 21.45	*	179.77 ± 14.23	ns	# #
Lysosomes	242.88 ± 23.39	202.89 ± 10.31	ns	186.85 ± 27.89	ns	ns

Values are presented as mean ± SEM, n > 9. Statistical analysis: Difference was analysed by one-way ANOVA followed by Tukey’s posthoc test
Values were considered statistically significant at * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001 between the cell lines (bEnd.3 vs. hCMEC/D3) # p ≤ 0.05, ## p ≤ 0.01, ### p ≤ 0.001
ns not significant, p^a significance when PBEC compared to bEnd.3, p^b significance when PBEC compared to hCMBEC/D3

ISSN: 2045-8118