Fig. 6

Lysosomal function. a Fluorescent intensity of Lysosensor green shows the acidification of lysosomes and matured late endosomes. Data are shown with box diagrams; the horizontal line represents the mean. The border of the box represents the error. b The bar graph shows the percentage of degraded ¹²⁵I-RAP per cells at different time points. Values are presented as mean ± SEM, n > 9. Values were considered statistically significant at *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001 between the cell lines (bEnd.3 vs. hCMEC/D3) and at ^#p ≤ 0.05, ^##p ≤ 0.01, ^###p ≤ 0.001 compared to the primary PBEC