From: The need for mathematical modelling of spatial drug distribution within the brain
Parameter | Value (rat) | Value (human) |
---|---|---|
Capillary radius (10−6 m) | ||
S, capillary surface area (m2) | 1.3 [216] | |
Intercapillary distance (10−6 m) | ||
Q, capillary blood flow rate (10−9 L min−1) | 4.82–8.83 [219] | 0.3–200 [114] |
Vbrain, brain volume (g) | 1400 [41] | |
Capillary blood flow velocity (10−4 m s−1) | – |