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Table 2 Growth hormone/IGF and diabetes

From: Comorbidity of diabetes mellitus in idiopathic normal pressure hydrocephalus: a systematic literature review

Year

Author

Findings

Type of study

2010

Teppala et al. [26]

Low serum IGF-1 levels were positively associated with diabetes***

National survey

1996

Hew et al. [8]

Decreased insulin sensitivity, decreased glucose storage rate, decreased glycogen synthase***

Controlled cross sectional study

2010

Schneider et al. [27]

Low or high serum levels of IGF-1 are associated with diabetes

Multiple prospective cohort studies

2005

Murray et al. [28]

Growth hormone resistant and insufficient adults are insulin resistant when stimulated with insulin***

Controlled cross sectional study

1984

Amiel et al. [29]

Low lGF-1 levels are positively associated with diabetes***

Controlled cross sectional study

2004

Jørgensen et al. [30]

Growth hormone deficient adults tend to be insulin resistant

Multiple case study

1995

Johansson et al. [31]

Adults with growth hormone deficiency were found to have normal fasting plasma insulin levels and insulin resistance***

Controlled cross sectional study

  1. Select sources related to growth hormone deficiency in adults and it’s associated to diabetes mellitus. Studies indicated with (***) involve an age and cohort matched non-iNPH control group and a statistically significant result