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Table 1 The quantitative results from the pre-shunt NPH and healthy control groups for both the aqueduct and prepontine cistern

From: Opposing CSF hydrodynamic trends found in the cerebral aqueduct and prepontine cistern following shunt treatment in patients with normal pressure hydrocephalus

 

Area (mm2)

Caudal max velocity (cm/s)

Cranial max velocity (cm/s)

Caudal mean flow (mL/min)

Cranial mean flow (mL/min)

SV (μL)

Aqueduct

 Pre-shunt

(n = 26)

8.0 [3.4]**

(5.1–13.7)

12.8 [8.3]*

(5.3–21.4)

8.4 [5.8]*

(4.3–17.0)

0.32 [0.23]**

(0.12–0.73)

0.26 [0.18]**

(0.09–0.57)

124.5 [94.5]**

(37.1–275.0)

 Control

(n = 10)

4.9 [1.7]

(3.1–7.4)

7.9 [4.5]

(5.3–15.0)

5.9 [2.2]

(3.8–8.2)

0.12 [0.07]

(0.06–0.19)

0.09 [0.04]

(0.05–0.15)

49.7 [32.3]

(23.1–90.5)

Cistern

 Pre-shunt

(n = 21)

58.6 [63.8]

(20.1–255.7)

6.3 [3.5]

(2.7–14.1)

4.9 [3.5]

(1.9–12.4)

0.78 [0.31]

(0.3–2.0)

0.43 [0.31]

(0.14–1.47)

293.5 [157.6]

(111.9–683.6)

 Control

(n = 8)

69.6 [22.0]

(31.1–92.2)

5.7 [1.8]

(3.1–7.5)

4.3 [1.9]

(2.1–8.3)

0.73 [0.35]

(0.4–0.8)

0.41 [0.22]

(0.27–0.63)

299.0 [171.5]

(181.2–418.7)

  1. Significant differences between NPH and control denoted by *(p < 0.05) and **(p < 0.001). For each metric the median [iqr] is shown. SV stroke volume