Region | Prevention | Efficacy | ||||||
---|---|---|---|---|---|---|---|---|
LF | LF TPM | HF | HF TPM | LF | LF TPM | HF | HF TPM | |
Whole brain | 1.102 ± 0.495 | 1.599 ± 1.160 | 3.174 ± 2.237a | 0.667 ± 0.413b | 0.883 ± 0.452 | 0.927 ± 0.473 | 1.672 ± 0.719a | 0.534 ± 0.096b |
Retina | 18.20 ± 7.654 | 21.37 ± 8.186 | 38.46 ± 20.53a | 29.98 ± 21.77a | 19.27 ± 7.943 | 31.13 ± 8.985 | 36.40 ± 11.65a | 29.62 ± 8.061 |
Vitreous humor | 3.941 ± 1.141 | 3.591 ± 1.513 | 6.062 ± 1.613a | 6.277 ± 2.636a | 5.398 ± 2.516 | 8.791 ± 4.617 | 7.917 ± 5.659 | 6.694 ± 3.447 |
Olfactory bulb | 2.110 ± 1.677 | 1.701 ± 0.789 | 2.267 ± 1.871 | 2.696 ± 1.483 | 1.697 ± 0.392 | 1.326 ± 0.653 | 2.383 ± 1.321 | 1.486 ± 0.547 |
Striatum | 1.892 ± 0.995 | 1.746 ± 1.905 | 1.840 ± 1.167 | 1.976 ± 1.669 | 0.795 ± 0.770 | 0.681 ± 0.512 | 0.823 ± 0.776 | 0.412 ± 0.273 |
Frontal cortex | 0.861 ± 0.815 | 1.081 ± 0.799 | 2.079 ± 1.736 | 0.949 ± 0.589 | 0.752 ± 0.344 | 0.773 ± 0.356 | 1.241 ± 0.765 | 0.522 ± 0.090b |
Hypothalamus | 1.528 ± 0.411 | 2.506 ± 2.400 | 16.41 ± 13.15a | 3.123 ± 2.274b | 0.815 ± 1.025 | 0.659 ± 0.667 | 0.223 ± 0.397 | 0.579 ± 0.436 |
Hippocampus | 0.630 ± 0.538 | 2.759 ± 2.324 | 3.603 ± 3.855 | 0.984 ± 0.765 | 0.598 ± 0.458 | 1.094 ± 0.723 | 1.742 ± 1.112a | 0.339 ± 0.273b |
Thalamus | 1.196 ± 0.640 | 1.951 ± 1.424 | 3.094 ± 3.046 | 1.273 ± 1.366 | 0.594 ± 0.510 | 0.710 ± 0.316 | 1.328 ± 1.258 | 0.367 ± 0.219 |
Parietal cortex | 1.119 ± 0.665 | 1.615 ± 1.486 | 2.576 ± 2.362 | 0.871 ± 0.802 | 0.723 ± 0.412 | 0.745 ± 0.411 | 1.359 ± 1.050 | 0.371 ± 0.125b |
Occipital cortex | 1.314 ± 0.841 | 1.982 ± 1.370 | 2.817 ± 2.521 | 0.655 ± 0.406 | 1.070 ± 0.530 | 0.669 ± 0.547 | 1.103 ± 0.720 | 0.406 ± 0.233b |
Cerebellum | 0.738 ± 0.430 | 1.087 ± 1.029 | 2.851 ± 2.483a | 0.990 ± 1.150 | 1.072 ± 0.742 | 0.899 ± 0.470 | 0.908 ± 0.458 | 0.752 ± 0.495 |
Midbrain | 0.947 ± 0.825 | 1.908 ± 0.943 | 2.994 ± 2.301 | 1.936 ± 2.206 | 0.515 ± 0.288 | 0.799 ± 0.482 | 1.260 ± 0.791 | 0.289 ± 0.220b |
Pons-medulla | 1.472 ± 0.654 | 2.191 ± 1.267 | 3.057 ± 1.969 | 2.548 ± 1.490 | 1.361 ± 0.670 | 1.176 ± 0.420 | 1.671 ± 0.800 | 1.598 ± 2.272 |