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Fig. 3 | Fluids and Barriers of the CNS

Fig. 3

From: Benchmarking in vitro tissue-engineered blood–brain barrier models

Fig. 3

Schematic illustration of the equivalent circuit for the impedance of a confluent monolayer. Rpara—resistance associated with paracellular ion transport, Rm—resistance associated with ion transport across the cell membrane (i.e. through ion channels), Cm—capacitance associated with the cell membranes, Rs—resistance associated with the media. If Rpara > Rm then paracellular ion transport is negligible and TEER values are determined by the resistance (1/conductance) of the endothelial cell membranes

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