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Fig. 7 | Fluids and Barriers of the CNS

Fig. 7

From: Tunneling nanotubes evoke pericyte/endothelial communication during normal and tumoral angiogenesis

Fig. 7

Representative confocal microscopy images of human glioblastoma sections immunostained for CD31 and Col IV. a, c, e Col IV+ TNTs (arrows) connect capillary-like tumor vessels (V); note in c and e the weak CD31 staining of tumoral endothelial cells. b, d, f On the single Col IV channel (red) the continuity of TNTs is better shown. Nuclear counterstaining TOPRO-3. Scale bars a, b 25 µm; c–f, 20 µm

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