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Fig. 5 | Fluids and Barriers of the CNS

Fig. 5

From: Sex-specific differences in organic anion transporting polypeptide 1a4 (Oatp1a4) functional expression at the blood–brain barrier in Sprague–Dawley rats

Fig. 5

Differences in Oatp1a4 expression at the BBB in male and castrated male Sprague–Dawley rats. Western blot showed a previously reported Oatp1a4 band of 90 kDa and band related to tubulin at 50 kDa. While tubulin expression is the same between sexes, castrated males (C1–6) show an approximately 4.0-fold higher expression of Oatp1a4 as compared to control male animals (M1–6). Results are expressed as mean ± SD of the ratio of Oatp1a4 protein expression to tubulin protein expression from six animals per treatment group. MWM molecular weight marker. **p < 0.01

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