Fig. 3From: Dose escalation study of intravenous and intra-arterial N-acetylcysteine for the prevention of oto- and nephrotoxicity of cisplatin with a contrast-induced nephropathy model in patients with renal insufficiency N-Acetylcysteine pharmacokinetics: serum concentrations of N-acetylcysteine and glutathione at different dose levels and time intervals. Blood levels of N-acetylcysteine (upper row) showed a significant linear dose response, while gluthatione concentrations (lower row) were inconsistently elevated. IV intravenous, IA intra-arterial, NAC N-acetylcysteine, GSH glutathioneBack to article page