Skip to main content

Table 1 Examples of cell encapsulation for CNS and CNS-related diseases

From: Blood–brain barrier and foetal-onset hydrocephalus, with a view on potential novel treatments beyond managing CSF flow

Disease/model

Cells/experimental paradigm

Results and references

Alzheimer’s disease

NGF in rats and primates

Neuroprotection [164]

Parkinson’s disease

Neuropeptide Y in rats

Neuroprotection [165]

Huntington’s disease

Choroid plexus in rats

Neuroprotection [143]

Epilepsy

GDNF, BDNF in rats

Neuroprotection, Decreased seizures [166, 167]

Stroke/ischaemia

Choroid plexus in rats

Neuroprotection [168]

Acute and chronic pain

Chromaffin cells (catecholamines, opioids) in rats

Reduced pain [169]