Fig. 4
From: Barrier dysfunction or drainage reduction: differentiating causes of CSF protein increase
Albumin (a) and IgG (b) quotient distributions in the spinal cerebrospinal fluid. x is the normalized location on the rostro-caudal axis from lumbar (x = 0) to cervical space (x = 1) as illustrated in Fig. 3a. Quotients are obtained using spinal CSF drainage rates calculated as outlined in the “Methods” section. Permeability of the blood-CNS barrier to IgG is obtained using Eq. (7)