Cerebrospinal fluid (CSF) biomarkers of iron status are associated with CSF viral load, antiretroviral therapy, and demographic factors in HIV-infected adults

Table 4 Distributions of iron biomarkers in CSF in different CHARTER subpopulations

CSF biomarker	Whites (N = 178) Median (IQR)	Blacks (N = 174) Median (IQR)	Hispanics (N = 42) Median (IQR)	p-value, (compared groups)
Iron (µg/dL)	3.50 (2.12, 6.13)	2.60 (1.00, 4.88)	4.57 (2.00, 6.63)	<0.01 (W/B)^a n.s. (W/H)^b 0.01 (H/B)^c
Transferrin (µg/mL)	18.91 (11.26, 29.53)	16.64 (9.49, 26.63)	16.71 (10.69, 27.56)	0.06 (W/B)^a n.s. (W/H)^b n.s. (H/B)^c
H-ferritin (ng/mL)	3.02 (1.44, 4.84)	2.41 (1.42, 3.86)	2.61 (1.24, 4.00)	0.04 (W/B)^a n.s. (W/H)^b n.s. (H/B)^c

Self-reported ancestry (race/ethnicity) was reported as “Other” by 9 participants (not shown)
p-values < 0.05 (italics) are statistically significant
^aSelf-reported whites compared to black individuals
^bWhites compared to Hispanic individuals
^cHispanics compared to black individuals

ISSN: 2045-8118