Table 3 Regions of the peaks for significant clusters in TBSS analyses
| Â | Hemisphere | MNI coordinate (x, y, z) | T valuea | Cluster size |
|---|---|---|---|---|
A. FA for shunt responders (SR) at baseline compared to healthy controls (HC) | ||||
 Region | ||||
  Middle part of cingulum | Right | 5, −12, 35 | 6.88 | 7210 |
  Middle part of corpus callosum | Left | −10, −25, 38 | 5.56 |  |
  SWM of superior parietal lobule | Left | −22, −51, 56 | 5.33 |  |
  Posterior part of corpus callosum | Left | −10, −43, 33 | 5.31 |  |
  Posterior part of corpus callosum | Right | 12, −48, 20 | 6.29 | 713 |
  Posterior part of cingulum | Right | 10, −39, 37 | 4.63 |  |
  Splenium of corpus callosum | Right | 10, −46, 13 | 4.58 |  |
  SWM of precuneus | Right | 9, −56, 27 | 5.63 | 113 |
  SWM of superior parietal lobule | Right | 15, −47, 52 | 5.55 | 4177 |
  SWM of primary motor cortex | Right | 23, −27, 57 | 4.99 |  |
  SWM of cuneus | Right | 16, −74, 33 | 4.57 |  |
  SWM of frontal operculum | Right | 43, 4, 18 | 4.66 | 387 |
  SWM of frontal operculum | Right | 42, 20, 16 | 4.47 | 358 |
 Excluded regions | ||||
  SWM of frontal operculum | Right | 41, 22, 6 | 7.01 | 39 |
  Perithalamic white matter | Right | 6, −14, 7 | 5.68 | 8 |
B. MD for shunt responders (SR) at baseline compared to healthy controls (HC) | ||||
 Region | ||||
  SWM of primary motor cortex | Left | −30, −14, 53 | 3.72 | 118 |
  SWM of superior parietal lobule | Left | −13, −59, 49 | 3.48 | 119 |
  SWM of primary motor cortex | Right | 13, −20, 56 | 3.47 | 117 |
  SWM of precuneus | Right | 10, −53, 24 | 3.40 | 115 |
  SWM of orbitofrontal cortex | Left | −26, 21, −18 | 3.37 | 114 |
  SWM of lateral occipital cortex | Right | 38, −63, 27 | 3.35 | 111 |
  Cingulum (cingulate gyrus) | Right | 7, −26, 37 | 3.01 | 106 |
  Cerebral peduncle | Left | −10, −17, −7 | 2.74 | 108 |
  SWM of middle temporal gyrus | Right | 51, −42, 4 | 2.74 | 101 |
  External capsule | Right | 23, 20, −4 | 2.73 | 112 |
  SWM of superior frontal gyrus | Left | −18, −1, 47 | 2.63 | 103 |
  SWM of superior parietal lobule | Right | 42, −53, 39 | 2.58 | 94 |
  Posterior corona radiata | Right | 35, −40, 36 | 2.43 | 87 |
  Superior longitudinal fasciculus | Left | −30, 15, 30 | 2.38 | 100 |
  Perithalamic white matter | Left | −18, −22, 9 | 2.32 | 83 |
  SWM of inferior parietal lobule | Right | 58, −28, 31 | 2.28 | 105 |
  SWM of superior temporal gyrus | Right | 51, −16, −2 | 2.17 | 98 |
  SWM of primary sensory cortex | Left | −9, −45, 59 | 2.14 | 39 |
  SWM of precuneus | Left | −8, −58, 42 | 2.10 | 96 |
 Excluded regions | ||||
  Cingulum (hippocampus) | Right | 26, −41, −6 | 14.4 | 120 |
  Fornix | Right | 3, −20, 20 | 10.6 | 120 |
  Fornix | Left | 0, −20, 21 | 10.6 |  |
  SWM of frontal operculum | Right | 54, −10, 14 | 5.57 | 116 |
C. FA in shunt responders (SR) post-operation compared to baseline | ||||
 Corona radiata | Left | −27, −10, 15 | 6.93b | 66 |