Table 2 Changes in clinical and MRI variables after shunt placement

A. Shunt responders (SR, n = 20)

 TUG, mean (SD)

  Time to complete (s)

14.7 (4.1)

11.2 (4.3)

19

<0.001

  Number of steps

21.9 (7.0)

18.1 (7.2)

19

0.001

 iNPHGS, median (range)

  Gait disturbance

2.0 (2–3)

1.0 (0–3)

<0.001

  Cognitive disturbance

3.0 (0–3)

2.0 (0–3)

0.001

  Urinary disturbance

1.5 (0–3)

0.0 (0–2)

0.004

  Total

6.5 (2–9)

3.0 (1–7)

<0.001

  MMSE, mean (SD)

21.5 (4.6)

24.0 (4.3)

19

0.008

  FAB, mean (SD)

10.7 (2.3)

12.9 (3.1)

19

0.002

  Left VV/ICV ratio (%), mean (SD)

8.29 (1.99)

6.59 (2.03)

19

<0.001

  Left hemispheric FA, mean (SD)

0.386 (0.022)

0.382 (0.026)

19

NS

  Left hemispheric MD (×10⁻³ mm²/s), mean (SD)

0.813 (0.036)

0.816 (0.035)

19

NS

  Mean FA of the left corona radiata, mean (SD)

0.624 (0.041)

0.592 (0.048)

19

<0.001

B. Shunt non-responders (SNR, n = 8)

 TUG, mean (SD)

  Time to complete (s)

15.6 (3.1)

14.2 (3.5)

7

NS

  Number of steps

22.6 (4.0)

20.5 (5.0)

7

NS

 iNPHGS, median (range)

  Gait disturbance

2.0 (1–4)

2.0 (1–4)

NS

  Cognitive disturbance

2.5 (1–3)

2.0 (1–3)

NS

  Urinary disturbance

2.0 (0–4)

2.0 (0–4)

NS

  Total

7.0 (4–9)

7.0 (4–9)

NS

  MMSE, mean (SD)

22.3 (5.0)

22.3 (5.0)

7

NS

  FAB, mean (SD)

11.0 (3.8)

11.0 (3.7)

7

NS

  Left VV/ICV ratio (%), mean (SD)

7.19 (1.99)

6.40 (1.79)

7

0.005

  Left Hemispheric FA, mean (SD)

0.380 (0.024)

0.375 (0.030)

7

NS

  Left Hemispheric MD (×10⁻³ mm²/s), mean (SD)

0.829 (0.068)

0.876 (0.099)

7

NS

  Mean FA of the left corona radiata, mean (SD)

0.612 (0.043)

0.607 (0.044)

7

NS