Fig. 2From: Cerebral hypoxia/ischemia selectively disrupts tight junctions complexes in stem cell-derived human brain microvascular endothelial cellsCobalt-chloride treatment impact monolayer integrity in iPSC-derived BMECs. Representative immunocytochemistry micrograph pictures of IMR90-derived BMECs monolayers in presence of CoCl2. Cells were treated with different CoCl2 concentrations. Note the presence of irregular patterning in TJ proteins (claudin-5 and occludin) as marked by asterisks at 30 µM treatment and a complete disruption at 100 µM. Scale bar = 20 µmBack to article page