Fig. 4

Decorin prevented myelin loss in the caudal internal capsule. a Representative images comparing caudal internal capsule MBP immunostaining (green) across the four experimental groups. Myelin organisation was better maintained with decorin use. b A bar graph displaying the mean percentage of MBP positive pixels above threshold in the internal capsule across the four experimental groups. Decreased MBP levels were present in kaolin and kaolin + PBS rats which was incompletely attenuated with decorin treatment; error bars represent the standard error of the mean, *p < 0.05, **p < 0.01, ***p < 0.001; scale bar = 50 μm