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Table 1 Demographic and clinical data of enrolled patients

From: The intrathecal, polyspecific antiviral immune response in neurosarcoidosis, acute disseminated encephalomyelitis and autoimmune encephalitis compared to multiple sclerosis in a tertiary hospital cohort

Diagnosis Multiple sclerosis Neurosarcoidosis Autoimmune encephalitis Acute disseminated encephalomyelitis
n 33 22 19 8
Mean age in years (range; SD) 47.8 (23–73; 11.8) 54.7 (31–83; 15.0) 56.2 (31–84; 16.7) 30.6 (4–63; 17.8)
Gender, females in % 69.7 40.9 36.8 50.0
Additional clinical details MS types:
 RRMS: n = 14
 SPMS: n = 5
 PPMS: n = 14
Most frequent neurologic/radiologic syndromes:
 myelitis: n = 6
 subcortical cerebral lesions: n = 6
 hydrocephalus: n = 3
 brainstem nerve palsy: n = 3
 meningitis: n = 2
Detected antibodies against:
 VGKC: n = 12
 NMDAR: n = 5
 GAD: n = 2
 GABAB-R :n = 1 (1 patient had VGKC- and NMDAR-antibodies)
Neurologic syndromes in addition to encephalopathy:
 brainstem syndrome: n = 3
 hemisyndrome due to cerebral lesions: n = 3
 cerebellar syndrome: n = 1
 myelitis: n = 1
  1. n number of patients, SD standard deviation, RRMS relapsing-remitting multiple sclerosis, SPMS secondary progressive multiple sclerosis, PPMS primary progressive multiple sclerosis, VGKC voltage-gated potassium channel, NMDAR N-methyl-d-aspartate receptor, GAD glutamic acid decarboxylase GABA B -R γ-aminobutyric acid B receptor