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Fig. 5 | Fluids and Barriers of the CNS

Fig. 5

From: Clearance from the mouse brain by convection of interstitial fluid towards the ventricular system

Fig. 5

Three dimensional reconstruction of the vasculature with co-localized distribution of tracers in a mouse head after injection in the cisterna magna. a F-500 was found in the subarachnoid space and along the penetrating arteries of the brain. b TR-3 was observed in the same compartment, but less confined and also diffusely present in the brain parenchyma. This was particularly evident around the large arteries of the circle of Willis. c Outside the brain, a strong signal was found in the nasal turbinates and along the optic nerves. Maximum intensity projections of 50 images at the indicated levels of the vasculature and F-500 are shown in panels CE. Panels a, b: dorsal view; ce: coronal view. Scale bar 1 mm

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