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Fig. 3 | Fluids and Barriers of the CNS

Fig. 3

From: Clearance from the mouse brain by convection of interstitial fluid towards the ventricular system

Fig. 3

Three dimensional reconstruction of the vasculature and distribution of tracers in a mouse head after injection in the striatum. a F-500 is present at the injection site, the lateral ventricles and in the olfactory bulb. b TR-3 is present in the same compartments but could not be detected in the olfactory bulb. Panels CE represent maximum intensity projections of 50 images at the indicated levels shown in a of the vasculature and F-500. c F-500 reached the nasal turbinates through the cribriform plate. d F-500 distributed in the striatum, reached the external capsule (EC), and the contralateral ventricle (LV) via the ventricular system. e The aqueduct of sylvius showed F-500. Panels a, b: dorsal view. Panels ce: coronal view. Scale bar 1 mm

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