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Fig. 7 | Fluids and Barriers of the CNS

Fig. 7

From: Endotoxin-induced inflammation down-regulates l-type amino acid transporter 1 (LAT1) expression at the blood–brain barrier of male rats and mice

Fig. 7

LPS had no effect on LAT2 mRNA expression in the rat and mouse brain. A X-ray film images of radioactive LAT2 in situ hybridization from the rat forebrain. LAT2 is expressed in several neuronal populations and the choroid plexus, but its expression did not change after LPS administration. BLA basolateral amygdaloid nucleus, cp choroid plexus, PVH hypothalamic paraventricular nucleus. Scale bar 2 mm. B Darkfield emulsion autoradiography images from the rat cortex show no change in neuronal LAT2 mRNA expression after LPS. Scale bar 200 µm. C Similarly, no change in LAT2 hybridization signal was observed in neurons of the basolateral amygdaloid nucleus in mice. Scale bar 100 µm

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Fluids and Barriers of the CNS

ISSN: 2045-8118