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Figure 8 | Fluids and Barriers of the CNS

Figure 8

From: Cultured cells of the blood–brain barrier from apolipoprotein B-100 transgenic mice: effects of oxidized low-density lipoprotein treatment

Figure 8

Effects of low density lipoprotein (LDL) and oxLDL on membrane fluidity of brain endothelial cells measured as anisotropy. Effects of oxLDL or LDL treatment on the membrane fluidity of cultured brain endothelial cells from wild type (Wt) and ApoB-100 transgenic (Tg) mice. Effects were measured by TMA-DPH fluorescence anisotropy on cell suspensions after overnight treatment with 10 µg/ml LDL or oxLDL treatment. C untreated control, OX oxLDL treatment. Values presented are mean ± SD, n = 3. Statistical analysis: ANOVA followed by Dunnett and Bonferroni post-tests. Statistically significant differences: (a) p < 0.001 compared to wild type control; (b) p < 0.001 compared to LDL treated wild type cells; *p < 0.05; **p < 0.01; ***p < 0.001 wild type compared to transgenic group.

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Fluids and Barriers of the CNS

ISSN: 2045-8118