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Figure 3 | Fluids and Barriers of the CNS

Figure 3

From: Detection of oligoclonal IgG kappa and IgG lambda bands in cerebrospinal fluid and serum with Hevylite™ antibodies. comparison with the free light chain oligoclonal pattern

Figure 3

Isoelectric focusing/affinity-mediated immunoblotting analysis of IgG, IgGκ, IgGλ, free κ, and freeλ OCBs in a patient with multiple sclerosis (Case 4 in Table 1) using paired CSF (C) and serum (S) samples. Several CSF-restricted OCBs that were not seen in serum samples (arrowheads). Anode is at the top. Samples were analyzed on the same gel using a mixture of 6.2% Pharmalyte pH 3-10 and 1.7% Pharmalyte pH 8-10.5.

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