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Table 1 Baseline characteristics in shunt responders and non-responders measured before tap test.

From: The value of the cerebrospinal fluid tap test for predicting shunt effectiveness in idiopathic normal pressure hydrocephalus

 

Variables

responders (IQR)

non-responders(IQR)

p

1

Number of patients

80

20

 

2

Male/Female

44/36

14/6

NS

3

Age (years)*

75(71-78)

75(71.2-78.5)

NS

4

Evans index (%)*

35(33-38)

34.6(32.7-38)

NS

5

CSFP(cmH20)*

13(9-15)

12(8-12.8)

< 0.05

6

GS-Gait-pre*

2(2-3)

2(2-3)

NS

7

GS-Cogn-pre*

2(1-3)

2(1-3.7)

NS

8

GS-Urin-pre*

2(1-3.7)

2.1(1.4)

NS

9

GS-Total-pre*

6(4-9.7)

6(4-9.2)

NS

10

TUG-pre (sec)*

19.5(15-26.7)

20(18.2-27)

NS

11

MMSE-pre*

22.5(15-25.7)

25(18.2-27)

NS

12

SAE (patient numbers)

7

8

< 0.005

 

Pneumonia

0

3

 
 

Malignancy

1

1

 
 

Vascular events

3

1

 
 

Subdural effusion

1

0

 
 

Surgery-related**

0

2

 
 

Femoral fracture

2

1

 
  1. Abbreviations: IQR: interquartile range, CSFP: cerebrospinal fluid pressure at lumbar tap, GS-Gait-pre: iNPH grading scale for gait pre tap test, GS-Cogn-pre: iNPH grading scale for cognition pre tap test, GS-Urin-pre: iNPH grading scale for urinary function pre tap test, GS-Total-pre: sum of three grading scales, p:probability, TUG-pre: timed up-and-go test, MMSE: Mini-Mental State Examination, SAE: severe adverse events. *: median (25% and 75% IQR),:**: shunt malfunction and bowel injury